Kagawa Nutrition University
Osamu Hayashi, Ph.D., Professor
Kyoko Ishii, B.S., Lecturer
Laboratory of Immunochemistry


Ishii, K., Shi, Y., Katoh, T., Hayashi, O, : Effect of phycocyanin, one of the extracts of Spirulina, on differentiation of U937 and HL-60 human myeloid leukemia cell lines. J. Phys. Fit. Nutr. Immunol., 19(3), 222-232 (2009)

Hayashi, O., Katayanagi, Y., Ishii, K., and Kato, T.: Flow Cytometric analysis of age-related changes in intestine intraepithelial lymphocyte subsets and their functional preservation after feeding mice on Spirulina. J. Med. Food, 12(5), 982-989 (2009)

Hayashi, O. : Study on health effects of Spirulina as a dietary supplement (Japanese). Journal for the Integrated Study of Dietary Habits, 18(1), 19-24 (2007)

Hayashi, O., Ishii, K., and Kato, T.: Charpter 10 Spirulina and Antibody Production. In: Gershwin, M.E. & Belay, A. eds. Spirulina in Human Nutrition and Health. CRC Press Taylor & Francis Group, Boca Raton, FL, pp.205-226 (2007)

Hayashi, O., Murakami, N., Ishii, K., and Miyaji, N.: Influence of astaxanthin ingestion on the mucosal immune responses in adult and aged mice. J. Phys. Fit. Nutr. Immunol., 17, 12-22 (2007)

Hayashi, O., Ono, S., Ishii, K., Shi, Y., Hirahashi, T., Kato, T.: Enhancement of proliferation and differentiation in bone marrow hematopoietic cells by Spirulina (Arthrospira) platensis in mice. J. Appl. Phycol., 18, 47-56(2006)

Nemoto-Kawamura, C., Hirahashi, T., Nagai, T., Yamada, H., Kato, T., and Hayashi, O.: Phycocyanin enhances secretory IgA antibody response and suppresses allergic IgE antibody response in mice immunized with antigen-entrapped biodegradable microparticles. J. Nutr. Sci. Vitaminol. 50, 129-136(2004)

Nemoto-Kawamura, C., Ishii, K., Miyajima, H., Hiarahashi, Y., Kato, T., and Hayashi, O.: Effect of Spirulina phycocyanin ingestion on the mucosal antibody responses in mice (Japanese). J. Phys. Fit. Nutr. Immunol., 13, 102-111 (2003)

Ning, Y.B., Nemoto-Kawamura, C., Ishii, K., and Hayashi, O.: Age-related change of mouse Peyer's patch in scanning electron-microscopic observation and its relation to mucosal immune response (Japanese). J. Phys. Fit. Nutr. Immunol., 13, 90-101 (2003)

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